In the quest to unravel the mysteries of Alzheimer’s disease (AD), scientists have long focused on the role of amyloid …
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Astrocytes, Recycling, and the Brain-Derived Neurotrophic Factor
What can quantum dot technology reveal about how astrocytes recycle?
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Switching off to switch pacemaker cells on
What if we could stop implanting pacemakers and create biological pacemakers by turning existing cardiomyocytes into specialized pacemaker cells? And how could suppressing rebellious microRNAs help?
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What can a lemur tell us about our aging hearts?
Throughout your life, your heart will clock up around three billion beats, all thanks to the heart’s own pacemaker cells, …
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How Do Antidepressants Affect Adrenergic Receptors?
When you think about valium, or diazepam, antidepressants and anti-anxiolytics come to mind. If you have a background in pharmacology, …
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Can Neurotrophic Factor Antibodies Detect Subtle Pathological Processes?
Alomone’s MANF antibody detects acutely induced brain damage. Can it also detect subtle and gradually evolving pathologies?
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MANF and Alzheimer’s Disease
In this blog series exploring the role of mesencephalic astrocyte-derived neurotrophic factor (MANF), we’ve covered epilepsy and Parkinson’s disease. This installment will explore MANF and Alzheimer’s disease.
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The Role of MANF in Parkinson’s Disease
MANF is neuroprotective and an intriguing potential new therapeutic for Parkinson’s disease.
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Astrocytes in Epilepsy: Friend or Foe?
Astrocytes expressing MANF may be neuroprotective in a mouse model of epilepsy.
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Better Research, Bad Eggs, and Thoughtful Controls
We need controls in research. We need to pay close attention to our assays, reagents, and the pathways we affect. …
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Detailed and Transparent Antibody Information – For You
You have a lot more information about antibody products than you might think. “What was the immunogen used?” “How do …
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DNA-PAINT and Super-Resolution Microscopy
Breaking light’s diffraction limit, spectrally unlimited multiplexing, and probing single-molecule events with DNA-PAINT You probably already know a bit about …
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Proton-Activated Chloride Channel 1 and Lyso-PS Receptors
New products are here for those of you working in neuro, immunology, and membrane protein fields. It’s not every day …
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Custom Services: Your Research Your Way
When your research needs something special, we can make it for you. You know that protocol in the lab? The …
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Antibody Isotype Controls: What they are and why you need them
A look at the new FITC- and APC-conjugated rabbit IgG isotype control antibodies and why you should use them in …
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