Ion Channels in Epilepsy

• DL-AP5

  A Competitive NMDA Receptor Antagonist

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  Cat # D-140

  Source Synthetic

  MW 197.1

  Target NMDA receptors

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• DL-AP7

  An Antagonist of NMDA Receptors

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  Cat # D-200

  Source Synthetic

  MW 225.19

  Target NMDA receptors

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• α-Dendrotoxin

  A Blocker of K_V1.1, K_V1.2, K_V1.6 and ASIC Channels

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  Cat # D-350

  MW 7048 Da

  Target K_V1.1, K_V1.2, K_V1.6, ASIC channels

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• β-Dendrotoxin

  A Potent Blocker of K_V1.1 and K_V1.2 Channels

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  Cat # D-360

  MW ~7000 Da

  Target K_V1.1, K_V1.2 K⁺ channels

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• γ-Dendrotoxin

  A Potent Blocker of K_V1.1 and K_V1.2 Channels

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  Cat # D-370

  MW ~7000 Da

  Target K_V1.1, K_V1.2 K⁺ channels

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• δ-Dendrotoxin

  A Potent and Specific Blocker of K_V1.1 Channels and a Less Potent Blocker of K_ir1.1 (ROMK1) Channels

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  Cat # D-380

  MW 6568 Da

  Target K_V1.1, K_V1.6 and K_ir1.1 K⁺ channels

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• Dendrotoxin-I

  A Potent Blocker of K_V1.1 and K_V1.2 Channels

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  Cat # D-390

  MW 7149 Da

  Target K_V1.1, K_V1.2 K⁺ channels

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• Dendrotoxin-K

  A Potent Blocker of K_V1.1 and K_V1.2 Channels

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  Cat # D-400

  MW 6560 Da

  Target K_V1.1, Kv1.1-containing heterooligomer.

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• Eliprodil

  An Antagonist of NMDA Receptors and N- and P-Type Ca_V Channels

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  Cat # E-155

  Source Synthetic

  MW 347.9

  Target NMDA receptors, N-, P-type Ca_V channels

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• Etbicyphat

  An Antagonist of GABA(A) Receptors

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  Cat # E-175

  Source Synthetic

  MW 178.12

  Target GABA(A) receptors

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• FTX-3.3

  A Blocker of P-Type Ca_V Channels

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  Cat # F-120

  Source Synthetic

  MW 273.4

  Target P-type Ca²⁺ channels

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• sFTX-3.3

  A Blocker of P-Type Ca_V Channels

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  Cat # F-130

  Source Synthetic

  MW 287.4

  Target P-type Ca²⁺ channels

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• GABA(A)-Compound 1b

  A Novel Antagonist of GABA(A) Receptors

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  Cat # CMG-004

  Source Synthetic

  MW 415.39

  Target GABA(A) receptors

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• Gabazine

  An Antagonist of GABA(A) and Glycine Receptors

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  Cat # G-215

  Source Synthetic

  MW 287.32

  Target GABA(A), Glycine receptors

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• Gabazine hydrobromide

  An Antagonist of GABA(A) and Glycine Receptors

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  Cat # G-216

  Source Synthetic

  MW 368.23

  Target GABA(A), Glycine receptors

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• GpTx-1

  A Blocker of Na_V1.7, Na_V1.5 and Na_V1.4 Na⁺ Channels

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  Cat # STG-400

  MW 4073.9 Da

  Target Na_V1.7, Na_V1.5, Na_V1.4 channels

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• GrTx1

  A Blocker of Na_V and K_V11.1 Channels

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  Cat # STG-250

  MW 3697 Da

  Target Na_V, K_V11.1 channels

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• GsAF-I

  A Blocker of TTX-Sensitive Na_V and K_V11.1 Channels

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  Cat # STG-300

  MW 3707.9 Da

  Target TTX-sensitive Na_V, K_V11.1 channels

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• GsAF-II

  A Blocker of TTX-Sensitive Na_V and K_V11.1 Channels

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  Cat # STG-350

  MW 3979.9 Da

  Target TTX-sensitive Na_V, K_V11.1 channels

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• GsMTx-4

  A Blocker of Na_V1.7, TRPC1, TRPC6 and Piezo1 Channels

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  Cat # STG-100

  MW 4096 Da

  Target Na_V1.7 channels, TRPC1, TRPC6, Piezo1

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