Cat #: EK-208
Size: 15 Vials
Form: Lyophilized
3-AQC Cat #: A-205_5 mg
Size:
5 mg
Source: Synthetic
MW: 395.41
Purity: >98%
Effective concentration
1-100 µM.
Activity
3-AQC is a potent and selective 5-HT3A receptor antagonist1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
100 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
Azasetron Cat #: A-240_5 mg
Size:
5 mg
Source: Synthetic
MW: 349.8
Purity: >98%
Effective concentration
0.1-100 nM.
Activity
Azasetron is a potent and selective 5-HT3 channel blocker with Ki ~2.9 nM1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
100-150 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
Azasetron hydrochloride Cat #: Y-100
Size:
5 mg
Source: Synthetic
MW: 386.3
Purity: >98%
Effective concentration
0.1-100 nM.
Activity
Azasetron hydrochloride is a potent 5-HT3 channel blocker with a Ki ~2.9 nM1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
100 mM in H2O. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
Bilobalide Cat #: B-145
Size:
10 mg
Source: Natural
MW: 326.3
Purity: >99.5%
Origin
Ginkgo biloba.
Effective concentration
1-100 µM.
Activity
Bilobalide is a 5-HT3A1 and GABAA2 channel blocker.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
100 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
Ginkgolide B Cat #: G-170
Size:
10 mg
Source: Natural
MW: 424.4
Purity: >98%
Origin
Ginkgo biloba.
Effective concentration
500-1000 µM.
Activity
Ginkgolide B is a 5-HT3A channel blocker1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
200 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
Lerisetron Cat #: L-175
Size:
5 mg
Source: Synthetic
MW: 292.4
Purity: >98%
Effective concentration
0.5-100 nM.
Activity
Lerisetron inhibits the 5-HT-induced Bezold-Jarisch reflex in anesthetized rats, pKi = 9.21.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
100-150 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
MCI-225 Cat #: M-190
Size:
5 mg
Source: Synthetic
MW: 328.4
Purity: >98%
Effective concentration
10 nM - 1 µM.
Activity
MCI-225 shows high affinity for the 5-HT3 receptor, Ki less than 100 nmol/L1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
30 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
MDL 72222 Cat #: M-155
Size:
10 mg
Source: Synthetic
MW: 314.2
Purity: >95%
Effective concentration
1 nM - 1µM.
Activity
MDL 72222 is an antagonist of 5-HT3 receptors1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
25 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
PU02 Cat #: P-165
Size:
5 mg
Source: Synthetic
MW: 292.4
Purity: >98%
Effective concentration
0.1-10 µM.
Activity
PU02 is a negative allosteric modulator of 5-HT31.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
200 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
SDZ 205-557 hydrochloride Cat #: S-145
Size:
5 mg
Source: Synthetic
MW: 337.2
Purity: >99%
Effective concentration
100 nM - 10 µM.
Activity
SDZ 205-557 hydrochloride is a 5-HT3 and 5-HT4 receptor antagonist1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
65 mg/ml in H2O. 100mg/ml in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
Talipexole dihydrochloride Cat #: B-140
Size:
5 mg
Source: Synthetic
MW: 282.23
Purity: >98%
Effective concentration
0.3-300 nM.
Activity
B-HT 920 is a blocker of 5-HT3 channels1. It is also an agonist of D2 dopamine receptors and α2-adrenoceptors.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
100 mM in H2O. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
Tropanyl-3,5-dimethylbenzoate Cat #: T-135
Size:
25 mg
Source: Synthetic
MW: 273.4
Purity: >99%
Effective concentration
1 nM - 1 µM.
Activity
Tropanyl-3,5-dimethylbenzoate is a 5-HT3 receptor antagonist1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
50-100 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
Tropisetron hydrochloride Cat #: T-125
Size:
10 mg
Source: Synthetic
MW: 320.76
Purity: >98%
Effective concentration
0.1-10 nM.
Activity
Tropisetron hydrochloride is a potent and selective 5-HT3A channel blocker with Ki ~ 2 nM1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
50 mg/ml in H2O. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
VUF 10166 Cat #: V-115
Size:
5 mg
Source: Synthetic
MW: 262.74
Purity: >99%
Effective concentration
0.05 nM – 100 nM.
Activity
VUF 10166 is a potent and selective 5-HT3A and B receptor antagonist1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
100 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
Zacopride hydrochloride Cat #: Z-110
Size:
5 mg
Source: Synthetic
MW: 346.25
Purity: >98%
Effective concentration
0.3-300 nM.
Activity
Zacopride hydrochloride is a highly potent 5-HT3 receptor antagonist (Ki = 0.38 nM) and 5-HT4 receptor agonist (Ki = 373 nM)1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
100 mM in H2O. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
For more information, please refer to individual certificate of analysis for each product.
For research purposes only, not for human use
