10 µM.

2,5-dimethylcelecoxib is a KCNQ channel opener in smooth muscle cells¹.

Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.

100 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).

Up to four weeks at 4°C or three months at -20°C.

10-500 µM.

cis-ACBD is a weak NMDA receptor agonist^1,2.

Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.

500 mM in H₂O. Centrifuge all product preparations before use (10,000 x g for 1 min).

Up to four weeks at 4°C or three months at -20°C.

Synthetic peptide

10-100 nM.

ATX-II potently modulates voltage-gated Na⁺ channel gating kinetics by delaying its inactivation and prolonging the action potential of excitable membranes. ATX-II has been used as a powerful activator of TTX-sensitive and insensitive Na⁺ channels in various excitable tissue and cell types^1-9.

Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.

Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min).

Up to four weeks at 4°C or three months at -20°C.

0.1-10 μM.

Capsaicin is one of the most powerful chemical agonists of the TRPV1 (transient receptor potential vanilloid) channel. It is a small lipophilic molecule derived from hot chili peppers that acts on sensory neurons by opening TRPV1, a principal transduction channel for nociception¹. Capsaicin acts directly on TRPV1², with half-maximal effective concentration of 711.9 nM in Xenopus oocytes³ and 0.29 μM in HEK293 cells⁴.

Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.

Ethanol. Centrifuge all product preparations before use (10000 x g 5 min).

Up to one week at 4°C or six months at -20°C.

1-5 mM.

GMQ is an ASIC modulator, an ASIC3 opener and also induces an acidic shift of the pH dependence of inactivation of ASIC1a, -1b, -2a, and -3¹.

Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.

50 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).

Up to four weeks at 4°C or three months at -20°C.

1-100 µM.

GV-58 is an opener of N- and P/Q-type Ca²⁺ channels¹.

Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.

100 mM in DMSO. Centrifuge all product preparations before use (10000 x g for 1 min).

Up to four weeks at 4°C or three months at -20°C.

0.1 - 10 µM.

NS-309 is a positive modulator of small- and intermediate- conductance Ca²⁺-activated K⁺ (K_Ca2 and K_Ca3.1) channels, with EC₅₀ values of 30 and 10 nM, respectively¹. NS-309 also blocks L-type Ca²⁺ channels with IC₅₀ value of 10 μM².

Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.

DMSO. Centrifuge all product preparations before use (10000 x g 5 min).

Up to four weeks at 4°C or three months at -20°C.

Synthetic peptide

1- 5 µM.

Waglerin-1 blocks ε subunit of muscle adult nAChR and modulates rodent GABA(A)/GABRA1 receptors^1,2.

Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.

Any other aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min).

Up to two weeks at 4°C or three months at -20°C.