Cat #: EK-101
Size: 15 Vials
Form: Lyophilized
Apamin Cat #: STA-200
Size:
0.5 mg
MW: 2028 Da
Purity: >98% (HPLC)
Net peptide content: 100%
Origin
Synthetic peptide
Effective concentration
100 nM - 1 µM.
Activity
Apamin is a blocker of voltage-independent Ca2+-activated K+ (SK) channels1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to two weeks at 4°C or two months at -20°C.
Charybdotoxin Cat #: STC-325
Size:
0.1 mg
MW: 4296 Da
Purity: >98% (HPLC)
Net peptide content: 100%
Origin
Synthetic peptide
Effective concentration
10-100 nM.
Activity
Charybdotoxin is a potent selective inhibitor of high conductance (maxi-K), different medium and small conductance Ca2+-activated K+ channels, as well as a voltage-dependent K+ channel (KV1.3)1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to two weeks at 4°C or three months at -20°C.
Iberiotoxin Cat #: STI-400
Size:
0.1 mg
MW: 4230.9 Da
Purity: >98% (HPLC)
Net peptide content: 100%
Origin
Synthetic peptide
Effective concentration
50-100 nM.
Activity
Iberiotoxin is a potent selective blocker of the high conductance Ca2+-activated K+ channels (maxi-K).
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to two weeks at 4°C or three months at -20°C.
Maurotoxin Cat #: STM-340
Size:
0.1 mg
MW: 3612 Da
Purity: >99% (HPLC)
Net peptide content: 100%
Origin
Synthetic peptide
Effective concentration
1-200 nM.
Activity
Maurotoxin activity was extensively assayed on a large array of K+ channels, including KCa (KCa1.1, KCa2.1, KCa2.2, KCa2.2, KCa3.1), KCNA (KCNA1, KCNA2 and KCNA3) and Shaker-B K+ currents and seems to be very potent blocker of either KCa3.1 and KCNA2 channels1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to two weeks at 4°C or three months at -20°C.
Kaliotoxin-1 Cat #: STK-370
Size:
0.1 mg
MW: 4150 Da
Purity: >98% (HPLC)
Net peptide content: 100%
Origin
Synthetic peptide
Effective concentration
10-100 nM.
Activity
Kaliotoxin-1 is a potent inhibitor of large conductance Ca2+-activated K+ channels (BKCa)1,2. Kaliotoxin-1 also binds the dendrotoxin sensitive voltage-dependent K+ channels (KV1.1, KV1.2 and KV1.3 nM)3.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to one week at 4°C or three months at -20°C.
NS-6180 Cat #: N-230
Size:
5 mg
Source: Synthetic
MW: 323.3
Purity: >98%
Effective concentration
10 nM – 1 μM.
Activity
NS-6180 blocks SK4 channels with IC50 of 9, 14 and 15 nM for rat, human and mouse erythrocyte KCa3.1 channels respectively1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
100mM DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
NS8593 Cat #: N-196
Size:
5 mg
Source: Synthetic
MW: 263.3
Purity: >98.5%
Effective concentration
100 nM -10 µM.
Activity
NS8593 is KCa2 (SK) channel blocker, with no activity towards KCa3.1 channels, with IC50~100 nM1,2. It also blocks TRPM7 channels3.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
100mM DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
OsK-1 Toxin Cat #: STO-150
Size:
0.1 mg
MW: 4205 Da
Purity: >98% (HPLC)
Net peptide content: 100%
Origin
Synthetic peptide
Effective concentration
5-100 nM.
Activity
OsK-1 inhibits KV1.1, KV1.2, KV1.3 channels potently and KCa3.1 channel moderately1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Any aqueous buffer.
Storage after reconstitution
Up to one week at 4°C or three months at -20°C.
Paxilline Cat #: P-450
Size:
0.45 mg
Source: Natural
MW: 435.6
Purity: >98% (HPLC)
Origin
Penicillium paxilli.
Effective concentration
10-100 nM.
Activity
Paxilline is a selective blocker of high-conductance Ca2+-activated (Maxi-K) K+ channels.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
DMSO or acetone. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to one week at 4°C or three months at -20°C.
Penitrem A Cat #: P-650
Size:
0.65 mg
Source: Natural
MW: 634.2
Purity: >98%
Origin
Penicillium palitans.
Effective concentration
10-100 nM.
Activity
Penitrem A is a selective blocker of KCa1.1 (high-conductance Ca2+-activated K+, BK) channels1. Penitrem A increases the spontaneous release of endogenous GABA (3-aminobutyric acid), and aspartate2.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
DMSO, methanol, acetone. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to one week at 4°C or three months at -20°C.
Scyllatoxin Cat #: STS-370
Size:
0.1 mg
MW: 3423 Da
Purity: >98% (HPLC)
Net peptide content: 100%
Origin
Synthetic peptide
Effective concentration
20-200 nM.
Activity
Scyllatoxin inhibits small conductance Ca2+-activated K+ channels (SK)1-3.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to two weeks at 4°C or three months at -20°C.
Slotoxin Cat #: STS-410
Size:
0.1 mg
MW: 4086 Da
Purity: >98% (HPLC)
Net peptide content: 100%
Origin
Synthetic peptide.
Effective concentration
10-100 nM.
Activity
Slotoxin inhibits the Maxi K+ (BKCa or mSlo, KCNMA1, KCa1.1) channels1. Slotoxin differentially blocks channels formed by the α1 subunit alone and channels formed by the α1 combined with auxiliary β subunits.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to one week at 4°C or three months at -20°C.
Tamapin Cat #: STT-400
Size:
0.1 mg
MW: 3458.16 Da
Purity: >98% (HPLC)
Net peptide content: 100%
Origin
Synthetic peptide
Effective concentration
500 pM - 50 nM.
Activity
Tamapin blocks KCa2 channels. Tamapin displays a remarkable selectivity for KCa2.2 versus KCa2.1 channels1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
TRAM 34 Cat #: T-105
Size:
5 mg
Source: Synthetic
MW: 344.8
Purity: >99%
Effective concentration
10 nM - 1 μM.
Activity
TRAM 34 is a potent and selective KCa3.1 (SK4, intermediate conductance Ca2+-activated K+) channel inhibitor1. As such, it is a powerful pharmacological tool that enables the determination of the roles played by KCa3.1 channels in different physiological systems ranging from activation of T lymphocytes to migration of endothelial cells2-3.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
Verruculogen Cat #: V-500
Size:
0.51 mg
Source: Natural
MW: 511.23
Purity: >98%
Origin
Penicillium simplicissimum.
Effective concentration
10-100 nM.
Activity
Verruculogen is a selective blocker of KCa1.1 (BK) channel. It belongs to a set of tremorgenic indole alkaloids1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
DMSO, methanol or acetone.
Storage after reconstitution
Up to two weeks at 4°C or three months at -20°C.
For more information, please refer to individual certificate of analysis for each product.
For research purposes only, not for human use
