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Home › Products › Ion Channels › K+ Channels › Voltage-Gated K+ Channels › Antibodies to KV Channels

Certificate of Analysis

KCNQ (KV7) Channel Antibody Explorer Kit

A Screening Package of KCNQ Channel Antibodies Economically Priced

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Cat #: AK-221
Size: 22 Vials
Form: Lyophilized

Application key:

CBE- Cell-based ELISA, FC- Flow cytometry, ICC- Immunocytochemistry, IE- Indirect ELISA, IF- Immunofluorescence, IFC- Indirect flow cytometry, IHC- Immunohistochemistry, IP- Immunoprecipitation, LCI- Live cell imaging, N- Neutralization, WB- Western blot

Species reactivity key:

H- Human, M- Mouse, R- Rat

Anti-KCNQ1 Antibody Cat #: APC-022

Size: 50 µl Host: Rabbit Type: Polyclonal Application: IC, IF, IH, IP, WB Reactivity: H, M, R
Immunogen
Peptide (C)TYEQLTVPRRGPDEGS, corresponding to amino acid residues 661-676 of human KCNQ1 (Accession P51787). Intracellular, C-terminus.
Homology
Rat, mouse - 14/16 amino acid residues identical.

KCNQ1 Blocking Peptide Cat #: BLP-PC022

Size: 40 µg

Guinea pig Anti-KCNQ1 Antibody Cat #: APC-022-GP (formerly AGP-050)

Size: 50 µl Host: Guinea Pig Type: Polyclonal Application: IH, WB Reactivity: H, M, R
Immunogen
Peptide (C)TYEQLTVPRRGPDEGS, corresponding to amino acid residues 661-676 of human KCNQ1 (Accession P51787). Intracellular, C-terminus.
Homology
Rat, mouse - 14/16 amino acid residues identical.

KCNQ1 Blocking Peptide Cat #: BLP-PC022

Size: 40 µg

Anti-KCNQ1 (extracellular) Antibody Cat #: APC-168

Size: 50 µl Host: Rabbit Type: Polyclonal Application: IC, IF, IFC, LCI, WB Reactivity: H, M, R
Immunogen
Peptide(C)EKDAVNESGRIEFG, corresponding to amino acid residues 284-297 of rat KCNQ1 (Accession Q9Z0N7). 3rd extracellular loop.
Homology
Mouse – identical; human – 13/14 amino acid residues identical.

KCNQ1 (extracellular) Blocking Peptide Cat #: BLP-PC168

Size: 40 µg

Anti-KCNQ2 Antibody Cat #: APC-050

Size: 50 µl Host: Rabbit Type: Polyclonal Application: IC, IF, IH, WB Reactivity: H, M, R
Immunogen
Peptide (C)RGPTITDKDRTKGPAE, corresponding to amino acid residues 578-593 of rat KCNQ2 (Accession O88943). Intracellular, C-terminus.
Homology
Mouse - identical; human - 15/16 amino acid residues identical.

KCNQ2 Blocking Peptide Cat #: BLP-PC050

Size: 40 µg

Anti-KCNQ3 Antibody Cat #: APC-051

Size: 50 µl Host: Rabbit Type: Polyclonal Application: IC, IF, IH, IP, WB Reactivity: M, R
Immunogen
Peptide AEGEKKEDNRYSDLKTIIC, corresponding to amino acid residues 668-686 of rat KCNQ3 (Accession O88944). Intracellular, C-terminal.
Homology
Mouse - identical; human - 18/19 amino acid residues identical.

KCNQ3 Blocking Peptide Cat #: BLP-PC051

Size: 40 µg

Anti-KCNQ4 Antibody Cat #: APC-164

Size: 50 µl Host: Rabbit Type: Polyclonal Application: IF, IH, WB Reactivity: H, M, R
Immunogen
Peptide (C)DRKTREKGDKGPSD, corresponding to amino acid residues 594-607 of mouse KCNQ4 (Accession Q9JK97). Intracellular, C-terminus.
Homology
Rat - identical; human - 12/14 amino acid residues identical.

KCNQ4 Blocking Peptide Cat #: BLP-PC164

Size: 40 µg

Anti-KCNQ5 Antibody Cat #: APC-155

Size: 50 µl Host: Rabbit Type: Polyclonal Application: IC, IF, IH, WB Reactivity: H, M, R
Immunogen
Peptide (C)RGSQDFYPKWRESK, corresponding to amino acid residues 856-869 of mouse KCNQ5 (Accession Q9JK45). Intracellular, C-terminus.
Homology
Human, rat - identical.

KCNQ5 Blocking Peptide Cat #: BLP-PC155

Size: 40 µg

Anti-KCNE1 (IsK) Antibody Cat #: APC-163

Size: 50 µl Host: Rabbit Type: Polyclonal Application: WB Reactivity: M, R
Immunogen
Peptide (C)RSKKLEHSHDPFN, corresponding to amino acid residues 68-80 of rat KCNE1 (Accession P15383). Intracellular, C-terminus.
Homology
Mouse, pig, dog – identical; human – 12/13 amino acid residues identical.

KCNE1/IsK Blocking Peptide Cat #: BLP-PC163

Size: 40 µg

Anti-KCNE2 (MiRP1) Antibody Cat #: APC-054

Size: 50 µl Host: Rabbit Type: Polyclonal Application: IC, IF, IH, IP, WB Reactivity: H, M, R
Immunogen
Peptide (C)IVEDWQQKYRSQILHLEDSK, corresponding to amino acid residues 88-107 of rat KCNE2 (Accession P63161). Intracellular, C-terminal domain.
Homology
Mouse - 18/20 amino acid residues identical; human - 16/20 amino acid residues identical; rabbit - 15/20 amino acid residues identical.

KCNE2/MiRP1 Blocking Peptide Cat #: BLP-PC054

Size: 40 µg

Anti-KCNE3 (MiRP2) Antibody Cat #: APC-118

Size: 50 µl Host: Rabbit Type: Polyclonal Application: IC, IF, IH, WB Reactivity: H, M, R
Immunogen
Peptide (C)RSRKVDKRSDPYH, corresponding to amino acid residues 81-93 of human KCNE3 (Accession Q9Y6H6). Intracellular, C-terminal part.
Homology
Rat, mouse, dog, pig -  identical.

KCNE3/MiRP2 Blocking Peptide Cat #: BLP-PC118

Size: 40 µg

Anti-KCNE4 (MiRP3) Antibody Cat #: APC-129

Size: 50 µl Host: Rabbit Type: Polyclonal Application: WB Reactivity: H, M, R
Immunogen
Peptide (C)GYMKSKRREKKSS, corresponding to amino acid residues 56-68 of mouse KCNE4 (Accession Q9WTW3). Intracellular, C-terminus.
Homology
Rat, human – identical.

KCNE4/MiRP3 Blocking Peptide Cat #: BLP-PC129

Size: 40 µg

Antibody Storage & Reconstitution Instructions

Storage before reconstitution

Lyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.

Reconstitution

Add deionized water, depending on the sample size.

Storage after reconstitution

The reconstituted solution can be stored at 4°C for up to 2 weeks. For longer periods, small aliquots should be stored at -20°C or below.
Avoid multiple freezing and thawing. The further dilutions should be made using a carrier protein such as BSA (1%). Centrifuge all antibody preparations before use (10000 × g 5 min).

Control antigen storage before reconstitution

Lyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.

Control antigen reconstitution

100 μl water.

Control antigen storage after reconstitution

-20ºC.

Preadsorption control

1 μg peptide per 1 μg antibody.

For research purposes only, not for human use

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  5. KCNQ (KV7) Channel Activator Explorer Kit (#EK-225)
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Resources

  • KCNQ (KV7) Channels

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