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Home › Products › Ion Channels › TRP Channels › TRPA1 Channel › Activators

Certificate of Analysis

TRPA1 Channel Activator Explorer Kit

A Screening Package of TRPA1 Channel Activators Economically Priced

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Cat #: EK-123
Size: 6 Vials
Form: Lyophilized

Capsiate Cat #: C-255

Size: 5 mg Source: Natural MW: 306.4 Purity: >94% (HPLC)
Origin
Capsicum annuum L.
Effective concentration
1-100 µM.
Activity
Capsiate activates TRPV1 and TRPA1 channels with EC50 = 3 µM1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Up 100 mM in DMSO. Centrifuge all product preparations before use (5,000 x g for 1 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.

Curcumin Cat #: C-230

Size: 5 g Source: Natural MW: 368.4 Purity: >96%
Origin
Curcuma longa L. root.
Effective concentration
10-200 µM.
Activity
Curcumin activates TRPA1 channels with an EC50 of 10 µM1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Up 100 mM in DMSO. Centrifuge all product preparations before use (5,000 x g for 1 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.

Ligustilide Cat #: L-170

Size: 10 mg Source: Natural MW: 190.2 Purity: >95%
Origin
Angelica sinensis.
Effective concentration
10-200 µM.
Activity
Ligustilide activates TRPA1 with an EC50 of 44 µM1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Up 100 mM in DMSO and 50 mM in Ethanol. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.

4-ONE Cat #: O-145

Size: 5 mg Source: Synthetic MW: 154.2 Purity: >97%
Effective concentration
1-100 µM.
Activity
4-ONE (4-Oxo-2-nonenal) is a lipid peroxidation product with multiple biological activities, shown to activate TRPA1 channels (EC50 = 1.9 µM)1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -80°C. Store tightly sealed.
Reconstitution
Supplied in oil form. Soluble in DMSO, methanol, ethanol.
Centrifuge all products before use (10000 x g 5 min).
Storage after reconstitution
-20°C.

Ononetin Cat #: O-135

Size: 50 mg Source: Synthetic MW: 258.27 Purity: >98%
Effective concentration
10-100 µM.
Activity
Ononetin is a deoxybenzoin, a potent blocker of TRPM3 channels (IC50 = 0.3 µM), also shown to activate TRPA1 channels at 10-100 µM1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C. Protect from light.
Reconstitution
Soluble in DMSO and ethanol.
Centrifuge all products before use (10000 x g 5 min).
Storage after reconstitution
Up to three months at -20°C.

Optovin Cat #: O-140

Size: 5 mg Source: Synthetic MW: 315.41 Purity: >98%
Effective concentration
10-100 µM.
Activity
Optovin is a photosensitive TRPA1 ligand that activates TRPA1 channels in vitro and facilitates repeated photoactivation of motor behaviors in vivo (EC50 = 2 µM) when reversibly activated by violet light (405 nm)1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C. Protect from light.
Reconstitution
Soluble in DMSO.
Centrifuge all products before use (10000 x g 5 min).
Storage after reconstitution
Up to three months at -20°C.
For more information, please refer to individual certificate of analysis for each product.
For research purposes only, not for human use

Related Products

  1. Anti-TRPA1 (extracellular) Antibody (#ACC-037)
  2. TRPA1 Channel Modulator Explorer Kit (#EK-120)
  3. TRPA1 Channel Blocker Explorer Kit (#EK-121)
  4. Mechanosensitive TRP Channel Antibody Explorer Kit (#AK-305)
  5. TRP Channel Antibodies for Pain Research Explorer Kit (#AK-370)
  6. TRPA1 Channel Basic Research Pack (#ESB-302)

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